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Measurable weight loss becomes apparent by week 2 to 3 for the majority of individuals
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The carriers of the loss-of-function GIP receptor variants, R190Q and E288G, display higher blood pressure and an increased tendency toward hypertension (99) but a comprehensive study of larger number of loss-of-function GIP receptor variants did not reveal similar effects on cardiovascular traits ( 2 , have highlighted the crucial role of endogenous GIP in the vascular system during meal digestion
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